Cytomegalovirus (CMV) retinitis is characterized by cell death and whitening of the retina, a pattern which looks like a pizza pie when viewed using special equipment to examine the interior of the eye. CMV retinitis is relatively common in patients infected with HIV.
The pizza pie appearance has also been likened to the look of cottage cheese and ketchup.
Banker AS: Posterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome. Indian J Ophthalmol, 2008 56(5):377-83. Go to reference
Pizza pie appearance in CMV retinitis