Under the light microscope in some cells of anaplastic large-cell
lymphoma (ALCL) the nucleus is ring-shaped with a ‘central opening’ thus resembling
a doughnut in look – doughnut cell.
ALCL is a rare cancer of the lymphocytes (the T-lymphocyte more precisely),
a kind of white blood cell, thus the designation lymphoma. Anaplastic refers to
cells that are abnormal in shape and function and large-cell pertains to the
relatively big cells of this cancer.
Depending on individual circumstances treatment for ALCL can
include, radiotherapy, chemotherapy, surgery, etc.
Reference:
Singh S, Gupta N, Tekta GR. Imprint cytology facilitating the diagnosis of primary cutaneous anaplastic large cell lymphoma of iliac fossa. J Cytol, 2012 29(4):267-9. Go to reference
Doughnut cell, doughnut
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