Sunday, February 15, 2015

Herringbone pattern

Under the light microscope in classic cases of the soft tissue cancerous tumor fibrosarcoma, the cells are arranged like the way the branching spines of a herring skeleton are arranged – herringbone architecture.
An architecture in which a column of cells resembling one herring skeleton is oriented one way and another separate cell column again resembling the skeleton is disposed in a different direction. Under the microscope there can be several such columns.
Fibrosarcoma is a rare cancer typically afflicting adults and can be treated with surgery, radiation or chemotherapy. The soft tissues are those which support, connect or surround the body’s other structures.
Reference:
Folpe AL. Fibrosarcoma: a review and update. Histopathology. 2014 64(1):12-25. Go to reference

Herring, sarcoma

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