Under the light microscope in classic cases of the soft tissue cancerous tumor fibrosarcoma, the cells are arranged like the way the branching spines of a herring skeleton are arranged – herringbone architecture.
An architecture in which a column of cells resembling one herring skeleton is oriented one way and another separate cell column again resembling the skeleton is disposed in a different direction. Under the microscope there can be several such columns.
Fibrosarcoma is a rare cancer typically afflicting adults and can be treated with surgery, radiation or chemotherapy. The soft tissues are those which support, connect or surround the body’s other structures.
Folpe AL. Fibrosarcoma: a review and update. Histopathology. 2014 64(1):12-25. Go to reference